Vladimir Dilman ? an internationally renowned endocrinologist, oncologist, and gerontologist whose name is firmly entrenched into the history of medical science. The eve of his 90th birth anniversary is a particularly appropriate time to remember the achievements of Vladimir Dilman. Prof. Dilman predicted what has become a cornerstone of modern theories of origin of many chronic age-associated diseases, highlighting the role of the increase of hypothalamic sensitivity to the inhibitory action of peripheral hormones in the development of main non-communicable diseases. The appreciation of the principal works of V. M. Dilman and his scientific biography not only increases our understanding of this subject, but provides a stimulus to independent research by younger generations and experienced specialists in the field of me. dical science and . practice, including e. ndocrinology and diabetology.