In the United States (US), homicide the leading cause of death among young Black men, Data on women of childbearing age, are sparse. We report trends in assault mortality in US women of childbearing age overall as well as by race, and weapon type from 1999 to 2018. We used death certificate data from the US Centres for Disease Control and Prevention and joinpoint regression analyses to test for trends. After years of decline, there were statistically significant increases from 2015-2018, particularly among non-Hispanic Black (NHB) women by firearms. Preventive medicine and community health efforts are necessary to curb this epidemic.