No abstract

A novel synthesis of halogenated gem-diboronates (X-CR(Bpin)2) was developed. The reagents are stable and easy to prepare in a large scale. Tetra-substituted halogenated gem-diboronates can be prepared in high yields when using alkylsubstituted gem-dihalides, providing a new strategy for the synthesis of new gem-diboron compounds.

No abstract

An effective method has been developed to facilitate the synthesis of amides and esters at ambient temperature within 5 min, in which a stable and easily accessible triflylpyridinium reagent is used. Remarkably, this method not only has a wide range of substrate compatibility but also could realize the scalable synthesis of peptide and ester via a continuous flow process. Moreover, excellent chirality retentions are presented during activation of carboxylic acid.