Bone sarcoidosis is usually considered a rare manifestation of multisystemic sarcoidosis. With the growing use of more sensitive imaging techniques, such as 18 F-FDG PET, the detection rate of bone involvement seems to be increasing. We describe the case of a woman presenting with fatigue and general malaise having multiple bone lesions on 18 F-FDG PET. A broad range of differential diagnoses was considered, including malignancy, infections, metabolic diseases and primary bone tumours, which may have delayed the diagnosis. Diagnostic work-up eventually led to an anatomopathological diagnosis of bone sarcoidosis. Immunosuppressive therapy is often necessary since sarcoid bone lesions -even asymptomatic -generally appear in more extensive forms of the disease with other organ involvement. KEYWORDS Sarcoidosis; bone; fluorine-18 fluorodeoxyglucose ( 18 F-FDG); positron emission tomography/computed tomography (PET/CT); magnetic resonance imaging (MRI)
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