Abstract. Multispectral imagery can be used for estimating production of oil palm fruit in a plantation. One of the multispectral imagery that capable for production estimation is Sentinel 2. Sentinel 2 is a free imagery that have great 10 m medium spatial resolution bands, which are red, green, blue, and near-infrared. These bands can be used to generate several generic vegetation index such as Ratio Vegetation Index (RVI) and normalized difference vegetation index (NDVI) also non-generic vegetation index such as modified soil adjusted vegetation index (MSAVI) and atmospherically resistant vegetation index (ARVI). Those vegetation index applied for estimating the production of oil palm fruit in PT. Perkebunan Nusantara VII's plantation at Rejosari, Natar. By-age separation method demonstrate that it has a better accuracy which is 87.5 % rather than normal method that fully transformed without being separated byage. The fully transformed method accuracy are 61.1 % for RVI, 59.1 % for NDVI, 55.3 % for MSAVI, and 62.1 % for ARVI.