Solution-processed colloidal quantum dots (CQDs) photodiodes
are
compatible for monolithic integration with silicon-based readout circuit,
enabling high-performance and low-cost infrared imaging. However,
operation stability of CQDs photodiodes has rarely been explored,
which is one of the main obstacles for CQDs imaging commercialization.
Here, we reveal that the performance deterioration of the CQDs photodiodes
under strong electric field at high temperature is mainly attributed
to ion migration in CQDs film, clearly clarified by aging photoconductors
based on each functional layer of CQDs photodiodes. The halide ion
migration through vacancy increases the defect density of the CQDs
layer and blocks device interfaces, resulting in increased dark current
density and postponed saturation voltage. We introduce polyimide (PI)
into CQDs film to efficiently block the pathway for halide ion migration.
As a result, the CQDs photodiodes with PI achieve greatly improved
operation stability over 27 h under 104 V/cm electric field
at 85 °C.
Adipose tissue is endocrine organ that responds by secreting numerous hormones that regulate metabolism in skeletal muscle and the liver. The aim of this study was to compare the levels of spexin and adiponectin in patients with non-alcoholic fatty liver and evaluate the relationship between circulating adipocytokines and insulin resistance. Two groups of subjects were evaluated: 41 non-alcoholic fatty liver subjects (age 35.17 ± 12.29 year, BMI 30.97 ± 2.75 kg/m2) and 38 normal controls (age 38.47 ± 11.63 year, BMI 22.83 ± 3.00 kg/m2). Plasma concentrations of spexin and adiponectin were determined using immunosorbent assay kits. Insulin resistance was assessed using the homeostasis model assessment (HOMA-IR) formula derived from fasting insulin and glucose levels. Compared to normal controls, plasma concentrations of spexin and adiponectin were significantly lower in patients with non-alcoholic fatty liver (P < 0.001). Spexin did not correlate with BMI but did significantly correlate with HOMA-IR (r = -0.368; P = 0.018) and adiponectin (r = 0.378; P = 0.043), and this correlation remained significant after adjustment for gender and BMI. In this small group of patients with non-alcoholic fatty liver we demonstrated that insulin resistance correlated strongly with spexin and adiponectin levels.
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