COVID‐19 healthcare workers (HCW) require frequent hand‐washing and personal protective equipment(PPE) to prevent infection. However evidence is emerging that these practices are causing adverse effects on their skin integrity. A single centre cross sectional study of HCW from an Irish hospital was undertaken to evaluate the degree of COVID‐19 related dermatitis between April and May 2020. Out of 270 participants surveyed, 223(82.6%) reported symptoms of dermatitis. Hands were the most commonly affected site(76.47%) and the most frequently reported symptom was dry skin(75.37%). 268(99.26%) HCW increased hand‐washing frequency, however 122(45.35%) denied using emollients. 24.7% of the dermatitis group cited a history of dermatitis compared to 4.3% of unaffected staff.(p <0.001)The dermatitis group recorded PPE usage for an average of 3.15 hours versus the non‐dermatitis group at 1.97 hours(p = 0.211). Promoting awareness of COVID‐19 related dermatitis is vital to highlight prevention and treatment for our frontline staff.
These findings suggest that at PDAI ≥ 7, every incremental increase in PDAI had a smaller detrimental impact on QoL. For the ABSIS, there was no significant difference in slopes before and after a given score, along with a higher P-value overall. Our results support previous findings 6 that the PDAI is superior to the ABSIS at capturing disease severity, especially at the lower end of disease activity (Figure 1c,d).To significantly improve QoL for patients with mucosal and nonmucosal PV, complete disease clearance may be necessary. Small amounts of worsening activity have an increasingly significant impact on QoL at the lower end of the spectrum. Above mild levels of activity, increasing activity has linear but detrimental smaller effects on QoL. The findings for patients with mucosal PV further support this, likely because oral erosions are painful and impact eating. Consistent with prior findings, 2 the Skindex-S best correlates with PDAI score in all patients.A notable limitation of this study is that our population had milder disease, with a median PDAI of 6Á75 and ABSIS of 11Á75. However, we are still able to show a change in QoL as the PDAI decreases, even at lower PDAI levels. Our findings have important clinical implications in determining appropriate outcomes for therapies. 7 Unlike dermatomyositis and systemic lupus erythematosus, 4 in patients with PV, complete clearance should be the goal.
Dealing with complex sustainability challenges requires an integrated approach to thinking and hence learning. Well-designed, integrated sustainability educational programs at the school level can have a significant positive impact on sensitizing students in this area. We present the case of a cross-curricular educational program designed and implemented at secondary level school with a focus on sustainability of material resources used in electronic products–a fast-growing sector with a significant environmental footprint. Over a 4-week period, teachers of five subjects (science, geography, business, technology and civic, social and political education) tailored their classes to focus on the topic of critical raw materials as it relates to these subjects. Examining a control group against the intervention group before and after the program, we use the New Ecological Paradigm (NEP) scale as a measure of students' environmental beliefs in order to find out the extent to which the program helped the cohort of students develop and retain such an ecological paradigm. Students' pro-NEP improved after the program, including on several facets, such as belief in limits to growth. Findings suggest that our cross-curricular approach was able to influence the young students' environmental orientation in a desirable direction.
superimposed upon chronic inflammation and heavy bacterial load, as demonstrated in our patient's biopsy. Other clinical manifestations are fever, headache, tender lymphadenopathy, orchitis, iridocyclitis and painful joints. ENL is the first manifestation of Hansen's disease, coming to medical attention, as in our case, in a third of the patients. 1 ENL can be precipitated by vaccination, pregnancy, lactation or current infection. 1 Reports of ENL following a vaccination are scarce, but include several cases following smallpox vaccination, 2 ICRC, 3 MIP 4 and influenza 5 vaccines, as detailed in Table 1.The BNT162b2 mRNA COVID-19 Vaccine is a lipid nanoparticle-formulated, nucleoside-modified mRNA vaccine encoding the prefusion spike glycoprotein of SARS-CoV-2, the virus that causes COVID-19. Adverse effects include pain, swelling and erythema at injection site, axillary lymphadenopathy and systemic symptoms. This is the first case report of ENL emergence after BNT162b2 mRNA COVID-19 vaccine. The early diagnosis and treatment in our patient were essential to minimize the likelihood of disability induced by this reaction, as this is often not reversible.As vaccination rates in leprosy endemic areas rise, so may the likelihood of higher rates of ENL. Attention should be given by health care providers.
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