The expression of the autism-related mutant R451C neuroligin3 activates the three branches of the unfolded protein response in neuronal-like PC12 cells and leads to up-regulation of the response target genes BiP and CHOP.

These findings support the hypothesis of pre-existing vulnerability (based on haploinsufficiency of reelin) to brain and behavioral disorders and regulative short- and long-term effects associated with nicotine modulation.

No abstract

Research on narcissism delineated two prevailing expressions of narcissistic strivings, namely grandiosity and vulnerability (Cain et al., 2008). Grandiosity is indicative of feelings of superiority, admiration seeking, and entitlement, closely reflecting the conception of narcissism in everyday language (Buss & Chiodo, 1991). Vulnerability, in contrast, describes anxious, defensive, and avoidant, yet entitled experience and behavior (Hart et al., 2017;