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Pytiriasiscapitis or dandruff is a condition of exofoliate peeling of the stratum corneum layer in the scalp. There are some factors that suspected to caused dandruff such as increased production of sebum, sensitivity individual against the sebum and microbiota activity in scalp, i.eMalasseziafurfur, Malassezia globosa, Pytirosporumovale, and Candida albicans. Therefore, treatment of dandruff is aimed to reduced sebum on the scalp and inhibit the growth of yeast population that causes dandruff. The juice of kaffir lime fruit (Citrus hystrix DC.) has been used by Indonesian people for tradisional therapy of dandruff. This study thas been conducted to find out antidandruff activities of M. furfur from kaffir lime fruit juice, peel, and leaves of kaffir lime tree extracted by ethanol, ethyl acetat, and n-hexan solvents. Antifungal activitiesis measured by inhibition zones using well diffusion agar methods.All citrus extracts showed antifungal activities against M. furfur with ethyl acetat solvent indicated the highest antidandruff activities, then followed by n-hexan, and ethanolicsolvent; although ethyl acetat and n-hexan was not significantly different (p>0.05).Leaves extract showed highest inhibition activities, then followed by fruit juice and peel extract, although leaves and fruit juice extracts was not significantly different (p>0.05).Part of the plant citrus consist of a alkaloid, saponin, tannin, phenolic, flavonoid, terpenoid, glikosida, and steroid. Antifungal activities suspected of phenolic, flavonoid, and terpenoid compounds. These results suggested that kaffir lime are effective against dandruff microbial and has potential as a herbal shampoo for dandruff treatment. AKTIVITAS ANTIKETOMBE EKSTRAK JERUK PURUTMENGGUNAKAN BEBERAPA JENIS PELARUT ABSTRAK Pytiriasiscapitisatau lebih dikenal sebagai ketombe, merupakan suatu kondisi eksfoliasi atau pengupasan berlebih pada lapisan stratum korneum di kulit kepala.Beberapa faktor yang diduga memacu timbulnya ketombe, antara lain: peningkatan produksi sebum, sensitivitas individu terhadap sebum dan aktivitas mikrobiota kulit kepala, sepertiMalassezia furfur, M. globosa.,Pytirosporumovale dan Candida albicans.Karena itu, pengobatan ketombe ditujukan untuk mengurangi sebum pada kulit kepala dan menghambat pertumbuhan populasi khamir penyebab ketombe.Air perasan buah jeruk purut (Citrus hystrixDC.) telah digunakan secara tradisional untuk mengatasi ketombe. Telah dilakukan penelitian untuk mengetahui aktivitas antifungi penyebab ketombe M. furfurmenggunakan metode difusi agar terhadap ekstrak air perasan buah, kulit buah dan daun jeruk purut dengan pelarut etanol, etil asetat, dan n-heksan.Seluruh ekstrak; ekstrak etanol, etil asetat, dan n-heksan dari air perasan buah, kulit buah, dan daun jeruk purut memiliki aktivitas penghambatan terhadap jamur penyebab ketombe M. furfur.Seluruh ekstrak jeruk purut mampu menghambat pertumbuhan M. furfur.Ekstrak etil asetat memberikan aktivitas penghambatan tertinggi, kemudian ekstrak n-heksan dan etanol; walaupun penghambatan ol...