One of the most important applications of sol–gel processing is in the preparation of thin films. Thin‐film formation is possible due to deposition of alkoxide followed by exposure to moisture. There are various methods for thin‐film coating or deposition using sol–gel technique. However, the basic steps are almost similar, which include exhausting, excess deposit material processing, and then drying. The physical properties and microstructure of films (density, porosity etc.) are governed by the structure of the colloidal species in the dispersion. The criteria governing the deposition along with the methods of deposition and their applications are discussed in this article.
The current review focuses on the comprehensive studies of platinum-based complexes that are known to exhibit anticancer properties. The capacity to perceive, to comprehend at the sub-atomic level, and to treat sicknesses has brought sufficient metal-particle work which constitutes an imperative part of therapeutic bioinorganic science. Understanding the biochemistry and sub-atomic science of detoxification mechanism of metals can help in advancing as well as enhancing the anticancer property of metal complexes for several types of a tumour. The classifications of complexes discussed have been done on the basis of Platinum oxidation states and binding sites of the ligands. Further background and current status of Pt(IV) complexes are briefly explained along with a special reference to Structural Activity Relationships and Mode of Action. The coordination chemistry of Pt(IV) has been summarised and Pt(IV) complexes are reviewed on the basis of binding of Pt(IV) with Human Serum Albumin and DNA. Finally, the results were summarized and concluded emphasizing on the most important features.
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