Under simple conditions which are easily satisfied, a single dose of 7,12-dimethylbenz(a)anthracenel induces mammary cancer in rat selectively, invariably, and rapidly.23 In this paper the stoichiometry of dose of 7,12-DMBA, and of frequency of its administration as well, are related to yield of mammary cancers under conditions wherein each dose of hydrocarbon evoked cancer in every rat and all doses were well tolerated by the recipient.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.