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Conjunctival melanoma is a rare malignant tumor with a recurrent character and metastatic potential. It is characterized in anatomopathology by a tumoral proliferation of atypical melanocytes. It can develop on a pre-existing lesion or appear on a healthy conjunctiva called "de novo" melanoma. The clinical aspect of melanoma is variable. It often appears as a pigmented lesion in relief, more or less nodular and vascularized, but it can also be achromatic. It can involve any portion of the conjunctiva and extend to the surface of the cornea. The involvement can be plurifocal.

Toxic epidermal necrolysis (TEN) is a rare but serious dermatological emergency characterized by diffuse exfoliation of the skin and mucous membranes [1], the epidermal loss is due to massive keratinocyte apoptosis and/or necroptosis. TEN is often caused by a drug mediating a specific TCR‐HLA interaction via the (pro)hapten, Frequently, the eyes and mucous membranes are affected [2]. We report a case of a successfully recovered TEN due to amoxicillin-clavulanic acid in a 60 years old female patient.

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