During total synthesis of pseudoxylallemycin A, an unstable intermediate was observed and appeared to be reactivated by coupling reagent by-products.

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A novel Maillard‐type condensation between a primary amine derived from D‐mannitol and a dihydropyranone, was used as a key step to access the unusual morpholine‐spiroketal acortatarin A. The synthetic approach also enabled access to a C‐2 analogue of acortatarin A, and can be used for the synthesis of related 2‐formylpyrrole natural products.

First described in the late 1960s, N-alkylsulfonylimines are heterocumulenes that participate in reactions with a range of 1,3-dipoles to afford interesting 3-, 4-, 5-, and 6-membered heterocycles. The distribution of adducts obtained suggests that multistage, stepwise mechanistic pathways rather than a concerted process are in operation.