The rate of AAA repair in octogenarians as well as EVAR increased over time. Perioperative outcome after intact AAA repair was stable over time, but improved after ruptured repair. Geographical differences in treatment of AAA remain.

The purpose of the study was to evaluate the evidence for an association between knee osteoarthritis (kneeOA) and physical work demands. Systematic searches were made, and epidemiological studies on kneeOA and heavy lifting, kneeling and climbing stairs published in 1966 to 2007 inclusive were reviewed. The quality of the studies was assessed and an overall evaluation of the degree of evidence of a causal relationship between kneeOA and physically demanding work was made, using specific criteria of the different degrees of evidence of causality. Limitations of the studies include few participants, use of different diagnostic criteria and a poor description of the exposure. It is concluded that moderate evidence was found for a relationship between kneeling, heavy lifting and kneeOA. For the combination of kneeling/squatting and heavy lifting the association seemed stronger than for kneeling/squatting or heavy lifting alone, but only a few studies were found concerning this relationship. Therefore the degree of evidence for a causal relationship was considered to be moderate. In the studies on the association between kneeOA and climbing stairs or ladders, there was an increased risk for kneeOA, but only a few studies were found and no dose-response relationship has been investigated. The evidence of a causal relationship is therefore considered to be limited.

Our study covered a 5-year period, and included all patients within a well-defined area who developed seizures after age 60 years. The dominant cause of seizures was a previous stroke, accounting for 32% of all cases. Tumors accounted for 14%, and the cause of seizures remained unknown in 25%. Seizures were recurrent in greater than 80% of patients with first seizure greater than 6 months after stroke. Fifteen of 21 patients with tumors had metastatic tumors. Of the six patients with primary brain tumors, five had malignant gliomas and one had a meningioma. We conclude that epilepsy with onset after age 60 years is more often symptomatic than is epilepsy in younger patients; since seizures were the first sign of a central nervous system (CNS) disease in half of the patients with brain tumors, careful investigation is necessary to reach a correct diagnosis.

This paper describes a novel low-inoculum S. aureus porcine model of IAO which was demonstrated to be reliable, reproducible and discriminative to human IAO, and represents a requested and valuable tool in orthopedic research. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:2211-2221, 2017.