Animals have developed strategies to respond to pathogens to avoid tissue injuries, but these strategies vary greatly among species such as mammals, amphibians and fishes. 1 Zebrafish (Danio rerio) is a teleost fish that, in contrast to mammals, present a high regenerative capacity even considering complex tissues, such as heart, retina, brain, spinal cord and fins. [2][3][4] It represents a relatively new animal model to study different aspects of biology mainly due to some aspects such as high fertility, rapid development, lower cost and maintenance space and the ease of genome editing. 5 Taking into

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