Background: Since the introduction of tyrosine kinase inhibitors (TKIs), the profile of pediatric relapse of Philadelphia chromosome-positive acute lymphoblastic leukemia Abbreviations: ALL, acute lymphoblastic leukemia; alloHSCT, allogenic hematopoietic stem cell transplantation; CIR, cumulative incidence of relapse; CNS, central nervous system; CR1, first complete remission; CR2, second complete remission; DFS, disease-free survival; EFS, event-free survival; KD, kinase domain; MRD, minimal residual disease; OS, overall survival; Ph + ALL, Philadelphia chromosome-positive pediatric acute lymphoblastic leukemia; SFCE, Société Française de lutte contre les Cancers et les leucémies de l'Enfant et de l'adolescent; TBI, total body irradiation; TKI, tyrosine kinase inhibitor.

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To describe the frequency and outcomes on the use of extracorporeal membrane oxygenation (ECMO) among critically ill neonates and children within a structured pediatric critical care network in the West of France. To assess the optimality of decision-making process for patients primarily admitted in non-ECMO centers.

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