No abstract

The objective of this study is to demonstrate the use of new polyunsaturated fatty derivatives for cutaneous applications. These new compounds present an analogue structure of cutaneous lipid, stabilize the polyunsaturated fatty acids (face to oxidation) and demonstrate specific biological activities. Three molecules described are Omega 6 fatty acid stabilized compound (O6FASC), the O3FASC and the O9FASC. The derivatives are synthesized via the same biotechnological process. This work describes the choice of final structure, the design of the biotechnological process and the free solvent enzymatic synthesis used for the synthesis of these three cutaneous lipid analogues. The restructuring effect of such analogues has been demonstrated with an in vivo study on volunteers. The stabilization of the O3FASC and O6FASC, and the biological activities of these three compounds are presented. The O6FASC shows very good results in anti-inflammatory effects; the O3FASC has anti-stress activities, whereas the O9FASC presents interesting results in improving elasticity and firmness. All these activity tests are presented in this work.

Le dossier Abstract L'Art de superviser des stagiaires is a training program of the Consortium national de formation en santé (CNFS) -University of Ottawa that aims to equip supervisors as they journey with trainees in their process of professionalization. These workshops, offered in classroom based or e-Learning formats to health and social service professionals who work with Francophone minority communities in Canada, cover themes such as performance evaluations and conflict management. Data collected via questionnaires indicate that following this training, supervisors feel more at ease with supervision and integrate learned strategies and guidance tools into their supervision.