Ovarian cancer (OC) represents a serious health problem worldwide. In Mexico, most OC patients are detected at late stages, consequently making OC one of the leading causes of death in women after reaching puberty. Personalized medicine (PM) provides an individualized therapeutic opportunity for treating each patient relying on "omic" tools to match the correct drug with the specific pathogenic genomic signature. PM can help predict the best therapeutic option for each affected woman suffering from OC. In recent years, Mexico has made contributions to the PM of OC; however, it still has a long way to go for its full implementation in the country's health system.
COVID-19 disease, in addition to causing the most common respiratory and systemic symptoms, such as cough and fever, has the ability to cause neurological manifestations such as headache, dizziness and altered mental status, which should not be overlooked by physicians when evaluating their patients, because even these manifestations suggest the presence of more severe disease, due to a poor immune response of the body against the virus. SARS-CoV2 infects cells through the Angiotensin-Converting Enzyme 2 (ACE2) receptor, because it is a receptor that is located in neurons, glial cells, and vascular endothelium, it is believed that the neurological symptoms are due to the direct invasion of the virus into the nervous system. Also, neurological complications to which this disease can lead have been identified, such as acute ischemic and hemorrhagic cerebrovascular events and direct infections to the central nervous system, such as meningoencephalitis and acute myelitis. For this reason, all physicians must take into account the neurological aspects involved in SARS-CoV2 infection, from the evaluation of suspected COVID-19 patients to the follow-up of confirmed cases throughout their disease.
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