Objective:The objective of this work was to establish whether the time of evolution and lifestyles were associated with adherence to treatment in a group of patients.Design and method:A cross-sectional analytical descriptive study was obtained using simple random sampling, a sample of 272 patients was obtained, of which 63% were female, average age of 55 years and average evolution time 7.5 years. The information was obtained using the treatment adherence questionnaire for cases of arterial hypertension factor II (Varela) modified for diabetics with a Cronbach alpha of 0.86. Data were processed with STATGRAPHIC Centurion 18 software and the R statistic. Hypotheses were tested with Wilcoxon rank test for evolution time and chi square test for lifestyles.Results:With a p-value < 0.05 for evolution time and the dimensions of the lifestyles studied: eating habits, practice of physical activity, it is concluded that adherence to diabetes treatments is associated with the time of evolution and with the practice of healthy lifestyles related to food and practice of physical activity.Conclusions:Adherence to treatments in patients with diabetes is associated with the time of evolution and the practice of good lifestyles. These two factors can be taken as predictors, which is why it must be rigorously monitored by health authorities