Background and Aims. Hyperferritinemia has been related with a wide spectrum of pathologies, including diabetes, cardiovascular disease, neurodegenerative disorders, and metabolic syndrome. The aim of this study was to investigate the association between hyperferritinemia and iron consumption. Methods and Results. Serum ferritin concentration was evaluated in 66 presumed healthy men, along with other clinical and biochemical markers of chronic diseases. A three-day food questionnaire was applied for nutrition information. Hyperferritinemia was a condition found in 13.4% of the volunteers analyzed. Significant correlations were found between serum ferritin concentration and metabolic syndrome parameters (HDL cholesterol, triglycerides, and fasting glucose) as well as an increase of the serum ferritin mean value with the number of risk factors of metabolic syndrome. Also, oxidative stress markers (carbonyl groups, AOPP, and glycated hemoglobin), hepatic damage markers (GGT, SGOT), and parameters related to insulin resistance (HOMA, blood insulin, and blood glucose) correlate significantly with serum ferritin. Volunteers had an excessive iron intake, principally by bread consumption. Analyses of food intake showed that red meat consumption correlates significantly with serum ferritin. Conclusion. Red meat consumption, metabolic syndrome, and chronic disease markers are associated with hyperferritinemia in a population of Chilean men.
Objectives: To compare the effectiveness of single (1 panel) vs. double (2 panels) phototherapy in reducing nonhemolytic hyperbilirubinemia in term newborns. Methods:Term newborns with hyperbilirubinemia were prospectively randomized to receive double or single phototherapy. Bilirubin levels were measured at admission and at 12-hour intervals, as well as at a follow-up 48 hours after discharge.Results: Thirty-seven patients received single and 40 double phototherapy. The mean decrease in bilirubin level in the first 24 hours of treatment was greater in the double phototherapy group (5.1±2.2 mg/dL vs. 4.3±2.1 mg/dL), but without statistical significance (p = 0.18). Readmission rates were similar and no adverse effects were found in either group.Conclusions: Double-surface was not more effective than single-surface phototherapy in the treatment of nonhemolytic hyperbilirubinemia in term newborns. However, our results suggest that double phototherapy may be more effective in those term newborns with higher bilirubin levels at admission. J Pediatr (Rio J). 2009;85(5):455-458:Phototherapy, newborns, hyperbilirubinemia, therapy, jaundice. ResumoObjetivo: Comparar a eficácia da fototerapia simples (1 painel) versus dupla (2 painéis) na redução da hiperbilirrubinemia não-hemolítica em recém-nascidos a termo. Métodos:Os recém-nascidos a termo foram randomizados prospectivamente para receber fototerapia simples ou dupla. Os níveis de bilirrubina foram medidos no momento da internação e em intervalos de 12 horas, assim como em seguimento 48 horas após a alta.Resultados: Trinta e sete pacientes receberam fototerapia simples, e 40, dupla. A redução média dos níveis de bilirrubina nas primeiras 24 horas de tratamento foi maior no grupo que recebeu fototerapia dupla (5,1±2,2 mg/dL versus 4,3±2,1 mg/dL), porém sem significância estatística (p = 0,18). As taxas de readmissão foram similares e nenhum dos grupos apresentou efeitos adversos. Conclusão:A fototerapia dupla não foi mais eficaz do que a fototerapia simples no tratamento da hiperbilirrubinemia não-hemolítica em recém-nascidos a termo. Entretanto, nossos resultados sugerem que a fototerapia dupla possa ser mais eficaz em recém-nascidos a termo com níveis de bilirrubina mais altos no momento da internação. J Pediatr (Rio J)
Introducción: La Diabetes Mellitus es una enfermedad de gran importancia a nivel de Salud Pública en todo el mundo, por ser una de las enfermedades no transmisibles más frecuentes que representa una gran carga económica para los sistemas de salud y la economía mundial. Objetivo: Diagnosticar los estilos de vida en pacientes con Diabetes mellitus tipo II que acuden al Centro Materno Infantil Enrique Ponce Luque, Babahoyo 2019. Metodología: La investigación está en el paradigma cuantitativo, de modalidad de campo, de tipo descriptiva con un diseño transversal. Se aplicó como técnica una encuesta y el instrumento fue el cuestionario IMEVID. La población fue de 103 pacientes y la muestra 85 pacientes con diabetes mellitus tipo II que asistieron al Centro. Resultados: se evidenció un inadecuado manejo de la historia clínica y del registro de la información de salud, inadecuado procedimiento de evaluación del estado de salud y baja calidad de atención a los pacientes. Conclusión: De un total de 85 pacientes con diabetes mellitus tipo II se obtuvieron 32 pacientes que presentaron un estilo de vida desfavorable; 28 tuvieron un estilo de vida poco favorable y 25 presentaron un estilo de vida favorable con un 38%, 33%, 29% respectivamente. La finalidad de esta investigación es concientizar a la población de estudio para mejorar los estilos de vida y disminuir el desarrollo de esta patología.
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