The majority of patients presented taste and olfactory changes soon after surgery independently of type of procedure. Patients submitted to LGBP referred more often a different smell in food. Higher %EWL was observed in patients presenting any food aversion, especially in the LGBP group.

No abstract

With increasing worldwide obesity rates, the surgery of choice has become the vertical transected gastric bypass, showing short-term improvements in weight loss and comorbidities. However, corresponding 10-year data regarding such endpoints is limited. The objective of this review was to assess such evidence. A literature search yielded a total of five studies, of which three had extractable data. Results revealed a reduction in the weighted mean body mass index (BMI), from a pre- to post-operative mean BMI of 47.5 kg/m(2) ± 2.0 to 33.4 kg/m(2) ± 4.4 at 10 years. The weighted mean excess weight loss was 61.4 % ± 13.5. Although these results suggest that weight reduction may be sustainable in the long term, this systematic review demonstrates a lack of strong evidence to support favorable long-term outcomes following vertical transected gastric bypass for obesity.

No abstract

Obesity is a major public health concern in Mexico and worldwide. Although the estimated heritability is high, common variants identified by genome-wide association studies explain only a small proportion of this heritability. A combination of linkage and association strategies could be a more robust and powerful approach to identify other obesity-susceptibility variants. We thus sought to identify novel genetic variants associated with obesity-related traits in the Mexican population by combining these methods. We performed a genome-wide linkage scan for body mass index (BMI) and other obesity-related phenotypes in 16 Mexican families using the Sequential Oligogenic Linkage Analysis Routines Program. Associated single-nucleotide polymorphisms (SNPs) were tested for associations in an independent cohort. Two suggestive BMI-linkage peaks (logarithm of odds ⩾1.5) were observed at chromosomal regions 11q13 and 13q22. Only rs614080 in the 11q13 region was significantly associated with BMI and related traits in these families. This association was also significant in an independent cohort of Mexican adults. Moreover, this variant was significantly associated with GSTP1 gene expression levels in adipose tissue. In conclusion, the rs614080 SNP near the GSTP1 gene was significantly associated with BMI and GSTP1 expression levels in the Mexican population.