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Temperature distribution in biological tissue is described by dual-phase lag model supplemented by appropriate boundary and initial conditions. Laser-tissue interactions are taken into account in the source function occurring in this model. The problem is solved using the finite difference method. Next, the Arrhenius integral which is a measure of tissue destruction is calculated. The inverse problem formulated here is to estimate the laser intensity assuring the destruction of this tissue region for which the Arrhenius integral exceeds the critical value.