This article presents the statistical data and results of own research on microbiological study of the udder secret from cows with subclinical and clinically expressed mastitis in 20 farms (27 dairy farms) of dairy direction of the Vologda region. The decisive value in the frequency of seeding from the affected shares of the udder of cows is coccal microflora, the largest share of which is occupied by conditionally pathogenic and pathogenic staphylococci (30,2% and 23,2%, respectively). Significant variability (from 0 to 100,0) of indicators of particular microflora from the secretion of the udder of cows with mastitis indicates significant differences in the etiology of the disease on farms region. Pathogenic and opportunistic staphylococci containing enterotoxins of types A, C, D, B and E from the udder secret indicates the potential danger of such milk for both calves and people. The article is executed in accordance with the state order № 0578-2014-0030.

The fight against mastitis was and remains one of the most serious problems in the dairy farming. The disease is widespread throughout Russia among cows of different breeds. According to our data, more than a half of the number of cows, up to 68.5% in a herd, go through mastitis during a year in the farms examined by us; 55.0% of them go through it from two to seven times. The coccal microflora has the decisive importance according to the frequency of isolation rate from the secretion of the udder of cows with mastitis -87.5% of the total number of isolated cultures with farm fluctuations from 40.0% to 100.0%. The test results of the vaccine “Streptostaphus” in three farms of the region made it possible to determine the most effective vaccination scheme for animals and to develop a “Method of specific prophylaxis of mastitis in cows.” The employees of the branch proposed a pattern of use of the complex drug “Amber-splenivitis” on pregnant animals with the aim of preventing mastitis in cows in the dry and postpartum periods. The use of antimicrobial drugs of prolonged action during the cows drying off period is advisable to take into account the sensitivity of microflora to them, released from the secretion of the udder of lactating cows of a single farm (complex). The prevention of massive mastitis in cows should include the implementation of measures aimed at increasing both the general resistance and specific reactivity of the cows organism.

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Êëþ÷åâûå ñëîâà: ìàñòèò êîðîâ, àíòèáèîòè÷åñêèå ïðåïàðàòû, êóðñ ëå÷åíèÿ, ÷óâñòâèòåëüíîñòü ìèêðîîðãàíèçìîâ. Ðåçþìå.  ýòèîëîãèè è ïàòîãåíåçå ìàñòèòà ó aeèâîòíûõ Àâäóåâñêàÿ, Í.Í. Àíàëèç ëå÷åíèÿ áîëüíûõ ìàñòèòîì êîðîâ â îäíîì èç õîçÿéñòâ Âîëîãîäñêîé îáëàñòè / Í.Í.

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