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Palladium(II) complex with 6-(2-hydroxy-5-methylphenyl)-3-(pyridin-2-yl)-1,2,4-triazin-5(2H)-one was synthesized for the first time. The ligand was prepared from 3-(pyridin-2-yl)-1,2,4-triazin-5(2H)-one and 4-methylphenol via nucleophilic substitution of hydrogen (S N H reaction). The complex was readily soluble in basic medium, and it effectively catalyzed Mizoroki-Heck reaction.Mizoroki-Heck reaction [1, 2], i.e., cross coupling of aryl halides with alkenes in the presence of palladium complexes (Scheme 1), has found wide application in modern organic synthesis [3].

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The title reaction leads regioselectively to a mixture of two isomeric 4‐aryl‐ and 5‐aryl‐substituted 2(1H)‐pyridones, in general.