Five allotypes, Lpm 1, Lpm 2, Lpm 3, Lpm 4, and Lpm 5, were detected by isoimmunization in mink sera. Immunoelectrophoresis, preparative ultracentrifugation, and histochemical tests for lipids and esterase permitted reference of these alloantigenic markers to a very high density alpha2-lipoprotein. Based on population analysis and breeding tests, five genetic units are postulated: Lpm1, Lpm4, Lpm3,4, Lpm1,2, and Lpm2,4,5. These units determine the polymorphism of the Lpm system and behave as Mendelian alleles.
Analysis of the frequencies of chromosomes carrying various classes of porcine endogenous retroviruses (PERVs) and combinations of these classes was performed in the swine species Sus scrofa L. by using maps constructed in two principal component coordinates. Four population clusters can be recognized in the maps. Cluster 1 is formed by wild boars,cluster 2 by domestic meat breeds, cluster 3 by meat-and-lard (universal) breeds, and cluster 4 by miniature pigs. The maps indicate that modern domesticated swine meat breeds are the closest to the wild type. Meat-and-lard domestic swine breeds are more distant from wild boars, and miniature pigs are diverged the most. The maps showed that microevolution processes associated with PERV carriership frequency had two basic dimensions, or vectors: the vector of fat deposition variation and the “minus” selection vector (determination of commercial traits). Thus, PERVs may cause variation in pig physiology
Mink Ldl antigen of serum low-density lipoprotein was demonstrated by alloantibodies. No genetic relation was found between Ldl and the Lpm system of very-high-density lipoprotein. The existence of an autosomal dominant gene, coding for the new alloantigenic marker, is postulated on the basis of mink breeding data.
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