The cotton leafworm, Spodoptera littoralis (Boisd) is a key polyphagous pest in Egypt. Without a hibernation period, the cotton leafworm is active all year. It was the most destructive insect pest of the great variation of important vegetables and field crops, approximately 112 species belonging to 4411families are attacked by this pest. Among the wide range of hosts, cotton, soybean, maize, wheat and vegetable crops (e.g., tomato, potato and strawberry) are processes in insects such as chitin synthesis inhibitors, juvenile hormone mimics, and ecdysone agonists.This group of insecticides consists of various compounds acting on insects of different orders by inhibiting chitin formation, thereby causing abnormal endocuticular deposition and abortive molting. The activity of biochemical sites (IPM). They have high pathogenicity for target pests. Safe for most non-target organisms, and have good integration with other pest control methods (Ibrahim et al.,.2010).The principal aim of the present study was to evaluate the toxic effect of Dipel DF, Jojoba and Chlorypyrifos in addition to untreated check control against.S. littoralis