The objective of the present study was to test the different hypotheses about factors related to the occurrence of brain tumors in children and adolescents. The case-control study of brain tumors was conducted in Belgrade (Serbia) from 1998 through 2000. The study group consisted of 60 newly diagnosed brain tumor patients and the same number of hospital controls. In the analysis conditional univariate and multivariate logistic regression were applied. According to the final model of multivariate analysis the following factors were significantly related to brain tumors: schooling of father <14 years (OR = 11.05, 95% CI 2.41-50.63, P = 0.002), mothers - housewives or workers versus clerks (OR = 2.62, 95% CI 1.06-6.57, P = 0.036), number of brothers and sisters greater than one (OR = 3.02, 95% CI 1.50-7.22, P = 0.001), and more frequent presence of malignant diseases, including brain tumors, in family history (OR = 3.54, 95% CI 1.30-9.60, P = 0.001). This case-control study was made to investigate different factors of possible importance for brain tumors in children and adolescents. Lower family social status, and more frequent occurrence of malignant tumors amongst relatives seem to be the factors that contribute the most to the higher risk of brain tumors.

Necrotizing otitis externa is a serious condition with uncertain prognosis. The suspicion of malignant external otitis should be raised in cases of resistance to topical treatment, especially in patient with predisposing factors. Evidence-based guideline for necrotizing otitis externa still doesn’t exist and treatment protocol should be adjusted to individual presentation of each patient.

AIm: AVM because of outstanding tendency toward bleeding, even though 20 times more rare then aneurysm on the blood vessels of the brain and her own specific anatomical structure even today represents big neurosurgical challenge. mAterIAl and methOds: Series which is shown here consists of 39 patients which were hospitalized in the institute for neurosurgery of the Clinical Center of Serbia in the period between 1995 and 2004. This group was exposed to symptomatic therapy or it was estimated that surgery, embolization and radio surgery. BulGulAr: Çoklu venöz drenajın tekrarlayıcı kanama gelişmesinde yüksek risk oluşturduğu (p<0.001) saptanmıştır. Çoklu arteriel besleyici bulunması ise çalma fenomenine yol açmaktadır (p<0.05). Hassas bölge yerleşimli ve boyutları 2.5 ile 5 cm arasında olan AVM'lerde eğer çoklu besleyici ve derin drenaj veni var ise, kanama riski artmaktadır (p<0.001).sOnuÇ: AVM'ler diğer damarsal sorunlara göre daha iyi huyludurlar. Her olgu kendi içinde değerlendirilmeli ve cerrahi, embolizasyon ve radyocerrahiden hangisinin uygun olacağına karar verilmelidir.

nema

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