Electrospinning is one of a method for fabricating nanometer to micrometre fibres. Some parameters that affect the formation of nanofibers in an electrospinning method such as solution, process, and environmental parameters. This research aims to synthesize and characterize polyethersulfone/polyacrylonitrile (PES/PAN) nanofibers and to analyze the effect of electrospinning parameters on PES/PAN nanofibers. PES/PAN fibres were prepared by dissolving PES with a concentration of 10% (w/w), 15% (w/w), 20% (w/w), and then added 0,5 gram of PAN. The results of fibre morphology with a variety of solutions showed the PPG1 fibre bead and the fibres for PPG2 and the fibre for PPG3, the morphological results of the PPG2 samples with variations in the tip collector distance indicated the fibre. The results of the diameter analysis showed that the effect of solution variation showed fibre for PPG1, PPG2, PPG3, namely 481 nm, 776 nm, 1339 nm, respectively while the diameter variation of the tip collector distance is 5 cm, 10 cm, 15 cm, namely 1266 nm, 860 nm, 401 nm, respectively and the voltage variation at 10 kV, 12 kV, 14 kV, namely 698 nm, 681 nm, 680 nm, respectively. The results of morphology and diameter show that the solution parameters and the electrospinning process affect the shape and diameter of the fibre. Fabricated fibres can be used as matrices in air filtration systems.