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isposable bioreactors have recently appeared as a technology of choice for culturing cells at large scale. That said, most existing disposable bioreactors are efficient for viral or protein biomanufacture but are not appropriately adapted for fragile stem cell production, which requires highly sensitive niche microenvironments. DThe upside of disposable bioreactors is that they can easily be operated with process control systems that allow monitoring of important culture parameters like gas flows, temperature, pH, dissolved oxygen levels, and -François Michiels, Ph.D., is a scientist and Matthieu Egloff (megloff@atmi.com) is product manager at ATMI LifeSciences. Web: www.atmi.com. Jean

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