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ABSTRACT. The base-line frequency of micronucleated cells was measured in g111 tissue of Mytilus galloprov~nc~ahs Lmk. from 2 ~Mediterranean areas (northern Tyrrhenian and northern Adriatic Seas), and turned out to be a function of water temperature and age of the animals.

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In mussels Mytilus galloprovincialis Lmk. exposed to the air or kept in oxygen-free seawater, the frequency of micronuclei detected in gill tissues significantly rises as a function of time. It is suggested that the genotoxic agent may b e a product of anaerobic metabolism, and the genotoxicity of propionic and acetic acid are shown, although the possibility that other substances may b e involved in the phenomenon is not excluded.