No abstract

No abstract

Objective To determine the placebo effect of trans-groups; 62% and 18% of patients had a >50% improvement in symptom score in the treated and urethral microwave thermotherapy (TUMT) in the treatment of benign prostatic enlargement (BPE).sham groups, respectively (P=0.001). The corresponding changes in flow rate were 36% and 11% Patients and methods A prospective, randomized shamcontrolled study in 93 patients (mean age 65, range (P=0.002), respectively. After 1 year, 63 patients were divided into those that had TUMT initally, those 50-88) was conducted at two centres comparing TUMT or a sham treatment. Patients randomized to that had sham initially but subsequently had TUMT and those whose sham procedure had led to sufficient receive sham treatment underwent the same initial procedure as for TUMT, but the complete procedure clinical improvement to require no further treatment. The two treated groups had a significant improvement was simulated on the visual display with no application of microwave energy. If the patient's condition over the sham group. Conclusion The benefit from TUMT cannot be due to a had not improved after 3 months, a second genuine TUMT treatment was given at the patient's request.placebo effect alone. Keywords Benign prostatic enlargement, placebo, Results After 3 months there were significant clinical and statistical differences in efficacy between the thermotherapy (TUMT) was probably ineffective in the treatment of BPE and Patients and methodsFrom June 1991 to December 1992, 93 men (mean age 65 years, range 50-88) were recruited into the study.

Objective To compare suprapubic and transurethral 60% of men were in the same LPURR class with either method. Using the transurethral method, 26% of methods of measuring intravesical pressure in a group of men undergoing investigation for lower urinary patients increased the LPURR class by one and 6% by two classes. Using the Abrams-GriÃths nomogram, tract symptoms (LUTS), to identify which urodynamic variables are aÂected by the presence of an urethral 17% moved from a classification of equivocal to obstructed and 3% from unobstructed to equivocal. catheter during the voiding phase, and consequently whether there is any change in the grading of bladder Using the criterion of a value of URA >29, 57% were obstructed using the suprapubic and 74% using the outflow obstruction (BOO) using the commonly recognised grading systems.transurethral method. Conclusion According to the method used, there were Patients and methods Thirty-five men with LUTS underwent both suprapubic and transurethral pressure-flow diÂerences in the classification of obstruction between the suprapubic and transurethral routes; transurethral studies during a single session. Standard pressure flow variables were measured in all patients with both studies tended to indicate greater obstruction. The interpretation of urodynamic studies should take into methods, enabling calculation of obstruction using the commonly used grading systems, i.e. the Abramsaccount the technique used and where the route is transurethral, the smallest catheter available should GriÃth number, linear passive urethral resistance ratio (LPURR) and urethral resistance algorithm (URA).be used.

Purpose: A retrospective study was done to investigate the long-term outcome of patients treated with lower energy transurethral microwave thermotherapy. Materials and Methods: A total of 305 patients with lower urinary tract symptoms and benign prostatic hypertrophy underwent transurethral microwave thermotherapy according to a similar protocol at 2 centers. Results: After 3 years of followup 133 patients who had undergone transurethral microwave thermotherapy alone were available for study. During this observation period significant symptomatic improvement from baseline and an improved maximum flow rate of 2.6 ml. per second were noted. Of the patients 125 underwent invasive or medical treatment. Conclusions: After 3 years of followup lower energy transurethral microwave thermotherapy showed significant and durable improvements in baseline parameters in 52% of the patients.