A few months delay before final treatment of a non-small-cell lung cancer seems to have an impact on the perioperative stage of the cancer, and thereby on the patients prognosis. A screening of asymptomatic risk-group patients will result in recognition of early lung cancer.

The intra- and interobserver agreement in cytological evaluation of endobiliary brushings from bile duct strictures is generally good. The rates of inadequate and suboptimal samples can probably be reduced by modifications of the brush design.

Background and Aims: longterm survival after curative resection for adenocarcinoma at the gastro-esophageal junction (gej) range between 18% and 50%. in the pivotal interin the pivotal intergroup-0116 phase iii trial by macdonald et all, adjuvant chemoradiotherapy improved both disease-free and overall survival in curatively resected patients with mainly gastric adenocarcinoma. We compared survival data for curatively resected patients with adenocarcinoma solely at the gastro-esophageal junction (gej), treated with surgery alone or surgery and adjuvant chemoradiotherapy. all patients underwent lewis-tanner operation with d1 node resection including coliac nodes (d1+). informations about recurrence and death were collected from the danish cancer register and the central death register. patients who died after experiencing severe complications after surgery were excluded from the survival analysis. patients with t0n0 or t1n0 were also excluded because patients of this category were not given adjuvant therapy according to the macdonald protocol.Results: patients with positive node status in the resected specimen, the 3-year diseasefree survival after adjuvant chemoradiotherapy (n = 91) or surgery alone (n = 43) was 24% and 37%, respectively. median time of survival was prolonged by 10 month in favour of those who received chemoradiotherapy. however, after controlling for the confounding effect of age and node status, only positive node status in the resected specimen had significant partial effect on survival.Conclusion: chemoradiotherapy according to the intergroup-0116 protocol might still be a reasonable option after curative resection in patients with gej adenocarcinomas and positive lymph node status, who did not receive neoadjuvant chemotherapy.

A case of non-invasive transitional cell tumours in the vagina in a 62-year-old woman is presented. Earlier, the patient had a left nephroureterectomy and a cystectomy performed due to invasive transitional cell tumours. The tumours in the vagina were located in an otherwise normal stratified squamous epithelium.