A total of 120 common carp Cyprinus carpio L. with average weight 20.45±1.24 gm/fish were assigned randomly into five groups of three replicates for each group, each replicate included 8 fishes. The fish were fed for 90 days on five diets that equal in isonitroenons 24.16% and isocaloric 1408.88 MJ/kg. Diet for control T1, local probiotic Iraq probiotic added at levels 5g/kg for diet T2, local probiotic added at 5g/kg from diet+5g/kg prebiotic which include fructo-Oligosacchardes FOS for diet T3, imported probiotic which include Enterococcus faecium added at 2g/kg diet for diet T4, imported probiotic which include E. faecium added at 2g/kg diet+2g/kg per diet prebiotic which include FOS for diet T5. The results showed there were significant distinction for T5 p<0.05 in growth parameter and food conversion and sufficiency rate FCR and FER and apparent coefficient digestibility ACD, there were no significant different between T5 and T4. The results of blood biochemical examination showed significant distinction for T4 from T1 and T2 in packed cell volume (PCV) and Hemoglobin Hb, there were no significant different between all treatment in erythrocyte and leukocyte count RBC and WBc.