No abstract

No abstract

Studies on Reactions of 3-Benzoyl-4-hydroxypyrido[3,2-e]-1,2-thiazines with Primary Amines and N-Methylhydrazine. -A series of pyrido[3,2-e]-1,2-thiazine enamine derivatives of type (III) and related pyrazolopyridothiazines (XI) as well as the model compounds (VI) and (VIII) are prepared as potential pharmaceuticals (antimycobacterial and analgesic activity). -(MALINKA*, W.; KARCZMARZYK, Z.; KACZMARZ, M.; SWIATEK, P.; URBANCZYK-LIPKOWSKA, Z.; Pol. J. Chem. 78 (2004) 6, 815-829; Dep. Chem. Drugs, Wroclaw Univ. Med., PL-50-137 Wroclaw, Pol.; Eng.) -M. Bohle 43-164

Thiazine derivatives Thiazine derivatives R 0610Preparation of Novel Derivatives of Pyridothiazine-1,1-dioxide and Their CNS an Antioxidant Properties. -Starting from isothiazolopyridine-1,1-dioxide (I), the title compounds (VI) possessing the 3-[4-(substituted-phenyl)piperazinyl]propyl or 3-(4-substituted-piperidinyl)propyl side chain at the thiazine nitrogen atom are prepared and evaluated for their acute toxicity and for their influence on the spontaneous locomotor activity, thiopental anaesthesia, carrageenan induced edema and analgesic activity. -(MALINKA*, W.; KACZMARZ, M.; FILIPEK, B.; SAPA, J.; GLOD, B.; Farmaco 57 (2002) 9, 737-746; Dep. Chem. Drugs, Wroclaw Univ. Med., PL-50-137 Wroclaw, Pol.; Eng.) -R. Langenstrassen 04-160