Studies were carried in the two seasons of 2017 and 2018 at the Experimental Farm of El-Sirw Agriculture Research Station, Damietta Governorate, Egypt. The main objective of study was to determine the effect of foliar spraying with some chemical substances during panicle initiation+ mid booting stages on rice growth, yield, yield attributes and grains quality characteristics of rice cv. Giza179. The experimental design was performed in randomized complete block design with four replications. Foliar application treatments were 1-Control (non-treated treatment), 2-Di ammonium phosphate spray (DAP 1.5%) 3-Potassium (K 2 O 1.5%) 4-N+K + mixture (1.5% for each) 5-Gibbrilic acid (GA 3 10ppm)+K + (1.5%) 6-Salicylic acid (SA 500ppm)+K(1.5%) 7-Humic acid (HA)+1.5%K). Salinity levels of experimental were 8.4 and 8.5 dSm-1 in both seasons, respectively. The plant growth, yield, yield components parameters, and grains quality characteristics were collected. The tested chemical substance significantly improved the studied characteristics rice grain quality, yields and yield contributes compared with the control treatment. Foliar spray with mixture of humic acid +K + at panicle initiation + mid booting stages was significantly the most efficient treatment in improving rice grain quality, growth and yields without significant difference with the mixture of N+K treatment regarding rice grain quality improvement. The mixture of humic+ K + could be recommended for improving rice quality and productivity of Giza 179 under salt stress.