This study aims to implement remote sensing to determine water quality parameters. Based on the water quality parameters measurements on February 5, 2021, and the LANDSAT 8 satellite images reflectance values, statistical models were generated by the RLM method: Stepwise Regression in Matlab software and digital models through QGIS and ArcGIS Pro GIS. The models obtained for pH, temperature, and turbidity were above 0.6 R2, while dissolved oxygen was above 0.8, showing a good correlation between in situ and estimated data. It is important to avoid cloudy conditions covering the study area because they limit the mathematical models’ application, altering or preventing the results from being generated. The implementation results of this type of technology are of great relevance for future projects, where water quality assessments can be made by using national and international regulations according to the use either for human consumption or for aquatic life protection.