Based on available RCTs, PRED monotherapy and PRED+AZA combination therapy are both viable induction therapies for AIH treatment naives and relapsers, while for maintenance therapy PRED+AZA and AZA therapy are superior to PRED monotherapy.
SUMMARY BackgroundTreatment failure occurs in 20% of autoimmune hepatitis patients on prednisolone and azathioprine (AZA). There is no established second line treatment.
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