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The side-effects of eyedrops employed for glaucoma treatment may first manifest after years of use, and can be localized [dermatitis, conjunctivitis (1), and nail pigmentation (2)] or generalized [bullous pemphigoid (3), toxic epidermal necrolysis (4), and anaphylactic reactions (5)].A 70-year-old man with glaucoma was treated with eyedrops containing timolol maleate and brimonidine tartrate for > 2 years. The patient presented with erythematous and oedematous pruritic lesions on both cheeks (Fig. 1a).

As cartilage grafts need a second surgical site, with consequent morbidity, the use of titanium mesh proves useful and safe in the reconstruction of nasal full-thickness defects. The results of our series of patients demonstrate the suitability of this material in the repair of nasal osteochondral defects, as well as its low rate of complications.

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