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The authors present a literature review using materials provided in the following databases: "MedLine", "PubMed", "Wiley Online Library", "Web of Science", "Oxford University Press", "SAGE Premier", dated 1995-2016. The paper describes the results of current international studies on the role of cytokine genes polymorphisms in the genesis of chronic cancer pain. We emphasize the role of inter-individual differences based on genetic polymorphism of cytokines and their receptors in personalized anesthetic care and accompanying therapy in oncology. (International Journal of Biomedicine. 2017;7(4):277-281.)

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The Chapter contains information about the prevalence of heart failure (HF) among patients in outpatient practice. The causal structure of HF, the prevalence of risk factors for HF, and the occurrence of a reduced ejection fraction are described. It describes the frequency of overdiagnosis of HF, the disease most often simulating its symptoms. The difficulties associated with laboratory and instrumental diagnostics of this syndrome are discussed. A pharmacological test for differential diagnosis of the causes of dyspnea in patients with suspected HF is described. Information is provided on the incidence of depressive and anxiety among the patients with this disease.