А review of domestic and foreign literature on compression methods for the formation of colonic anastomoses is presented in the paper.Despite advances in the improvement of the manual suture of the colon, the frequency of postoperative complications remains high – 68.7%, while mortality ranges from 1% to 26%. Thus, it was not possible to achieve the absolute reliability of the traditional manual suture in the formation of colonic anastomoses.Compression anastomosis has an advantage over manual. When forming an anastomosis using a compression method, a decrease in time was noted, ease of creating an anastomosis, a significant decrease in postoperative complications and a high quality of the formed anastomoses, confirmed by morphological studies.

Summarizing the experience of research and treatment of 218 patients (134 (61.5%) men and 84 (38.5%) women) with pathological symptoms frolicking after surgery on the stomach and duodenum. The average age of patients was (56.7 ± 13.7) years old. The authors formulated the obligatory scope of examination of patients to select possible options for reconstruction of the gastrointestinal tract. The results of the developed methods are demonstrated, confirming the need to restore the natural passage of food, and, if necessary, the creation of functionally active formations that prevent the occurrence of a retrograde pathological flow of contents from the distal parts of the digestive tract to the proximal.

Purpose of the study: to conduct a comparative analysis of endoscopic retrograde transpapillary interventions in patients with chronic opisthorchiasis and obstructive jaundice of various etiologies.Material and Methods. The results of treatment of 129 patients with chronic opisthorchiasis and obstructive jaundice of various etiologies who underwent transpapillary interventions to correct bile duct, were analyzed. In order to assess the condition of patients, general clinical methods and a set of laboratory and instrumental methods were used. The study was carried out in two groups, in the first endoscopic drainage of the bile ducts was carried out, in the second – either endoscopic papillosphincterotomy with choledocholitholite extraction, or endoscopic papillosphincterotomy with bougienage of the ducts. Each group of patients was divided into subgroups according to nosology: 1 – diseases of the biliary tract; 2 – oncological diseases of the hepatopancreatic zone; 3 – pancreatitis. Laboratory indicators before and after the application of minimally invasive interventions were compared.Results. The use of various methods of transpapillary interventions normalizes indicators of bilirubin, and aminotransferases in patients by 5–10 days. Endoscopic stenting of the ducts was the method of choice with cancers of the parasitic organs. With concomitant choledocholithiasis, the endoscopic papillosphincterotomy technique with subsequent lithotripsy and lithoextraction were used. Draining operations showed a good efficacy in the treatment of jaundice in the case of impossibility of removing the calculus. Endoscopic papillosphincterotomy with ductal bougienage was the operation of choice for streak tours of the common bile duct. With purulent cholangitis, endoscopic papillotomy with the installation of nasobiliary drainage and subsequent sanitation of the bile ducts was used.Conclusion. The use of endoscopic drainage has proven itself well in patients with obstructive jaundice of tumor etiology, as well as in patients with choledocholithiasis when it is impossible to remove the calculus. This surgery allows for quick normalization of the bilirubin level.

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The paper contains the results of an experimental study of the effect of ferroelectric composite polymer membranes on the healing process of purulent wounds. The membranes were formed by electrospinning based on vinylidene fluoride-terafluoroethylene copolymer, polyvinylpyrrolidone K17 (PVP) polymer, zinc oxide nanoparticles (ZnO). Five spinning solutions with different contents of PVP were prepared: 0, 5, 10, 20 and 40 mass %.The effect of the membranes was evaluated depending on the content of PVP. The conductivity and viscosity ofthe spinning solutions were determined. The structure of the formed membranes was studied. The diameter of the fibers forming the membranes was determined by scanning electron microscopy. The antibacterial activity of the membranes was evaluated. The ability of the developed membranes to heal a purulent wound was studied in experiments on laboratory animals.