Aim: This systematic review is specifically aimed to compare mammography and ultrasonography in early detection of breast cancer. For this systematic review, major purpose is to compare both screening methods and also analyze the performance of supplemental ultrasonography for early detection of breast cancer. Methodology: For this systematic review, total 23 studies are included which follow the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Electronic articles from year 2007 to from year 2017 on PUB Med, online Willey library, and Science Direct site were searched by using keywords related to sonographic and mammography imaging for breast cancer. Results: Out of 23 studies, 12 studies are conducted on women with dense breasts. Twenty studies performed their imaging with hand held ultrasound (HHUS). Out of twenty-three studies, sixteen studies followed BI-RADS procedures. In eleven studies that used joint methods, it was observed that mammography (MAM) has 65% whereas ultrasound (US) has 68% efficiency for early detection of breast cancer. 88% area under a cover (AUCs) among MAM and 98% among US imaging was observed. No major difference was found in sensitivity and specificity of both techniques. Conclusion: Study concludes that Ultrasound is more efficient to diagnose factors suggestive of breast cancer that cannot be detected on mammography. It also has the potential to evaluate cancer among dense breast women but unfortunately in some cases, it may cause a high recall rate. Keywords: Breast, Cancer, Mammography, Ultrasonography, Screening.

Objective: To know the usefulness of color and spectral doppler in evaluation of solid breast masses using vascularity and resistive index. Material and methods: We performed duplex doppler sonography on 100 patients presenting with breast mass. Resistive index and vascularity of the vessels were detected and analyzed and correlated with histopathological results. Results: 70% of the benign lesions were found having ri below 0.8 and 45 out of 50 patients had low vascularity.43 malignant lesions had high vascularity and 80% had ri above 0.8. Conclusion: High flow visualization on power doppler and indicates a higher possibility of malignancy lesions with ri greater than 0.8 gives high probability of malignancy.

Objective: The aim of this study was to assess the value of duplex ultrasound examination in establishing diagnosis in swollen lower limbs. Setting: This study was conducted at the Department of Diagnostic radiology Mayo hospital Lahore. Method: 50 consecutive patients presenting with leg swelling, submitted for colour Doppler sonography of the lower extremities were examined for deep vein thrombosis (DVT). Results: 46% of the patients were detected as having DVT , when examined through Doppler Ultrasonography. While 28% of the patients were not having any pathology in the limb.26% of the patients were having pathology other than DVT. Conclusion: The veins of the calf muscles are a common site of acute DVT and a source of pulmonary embolism. They should always be investigated in patients with leg swelling. Complete venous evaluation with duplex imaging can be very helpful in determination of underlying cause of the swelling.