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Rosai-Dorfmann disease manifests on the skin commonly as papules, nodules or rarely as infiltrated plaques. Authors report the case of a 27 year-old-man, presenting diffuse, budding and pediculated tumoral skin lesions associated with superficial and deep lymphadenaopathies and fever. The histopathological examination showed caracteristic features of emperipolesis. The Rosaï-Dorfman disease is remarkable in our case by its tumoral and profus presentation, as well as its pseudo-xanthomatous aspect.