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The aim of this study was to evaluate the antibacterial and antifungi activities of ethanolic and methanolic extracts from Chrysophyllum albidum stem bark. The crude extracts were screened against Staphylococcus aureus, Escherichia coli, Klebsiella, Candida albicans and Aspergillus niger at different concentrations (3.125 mg/mL, 6.25 mg/mL, 12.5 mg/mL, 25 mg/mL, 50 mg/mL and 100 mg/mL) using the agar well diffusion technique. The ethanolic extracts had stronger Original Research Article