This paper is aimed at presenting contemporary knowledge in the field of integral wheat protection against parasites, i.e. the use of cultural measures and genetic analyses directed at adequate use of breeding results, monitoring and forecasting of prevalent parasite growth and development with the aim of rational fungicide application. In addition, the paper suggests the proper use of biological measures through artificial infection with Pyrenophora tritici repentis (Ptr) in years not favourable for facultative parasite development. Growing of the varieties not lower than 85 cm with optimal stem growth ratio in regions with 550-650 mm precipitation, deep and complete soil cultivation plus nutrition before sowing in late October reduced the risk of facultative parasite appearance on lower and middle leaves by over 15%, which was considered useful because of the antagonism to obligate parasites. Severity of Puccinia triticina on last two leaves when facultative parasites were absent was increased at 60-70% as maximal level according to suggested SAGR. Nevertheless, we suggest growing of varieties with prolonged latency period resistant to Puccinia triticina. The aim is to avoid overaccumulation of resistance genes consequential through the decrease of wheat grain yielding potential. Genes facilitating toxin from Ptr spreading have to be excluded because of necessary antagonistic effect from the middle leaves. This implies gene for the obligate parasite specific resistance diversity of varieties in order to reduce the probability of simultaneous overcoming of resistance and avoid insurmountable changes in seed production. The final result of the proposed system should be the last two leaves with mostly minimal parasite appearance and the possibility of economical and efficient single curative treatment application once in ten years when facultative parasites are absent in spring or after the resistance of variety is overcome in standard conditions. The practical aim was also dependent on leaf rust development and green leaf area dissapearence forecasting models as well as balance between the size of the farm and equipment due to short deadlines

This paper deals with the resistance of twenty commercial winter wheat cultivars to common bunt causal agent (Tilletia tritici). Significant differences among the cultivars concerning the infection percent were observed, as well as the differences in the level of commercial cultivars' resistance to T. tritici. Most of the studied cultivars belonged to susceptible categories, and just few of them to the resistant ones. Cultivar Lasta was classified as highly resistant during the both investigation years in Kragujevac, while in Leposavić Lasta and Tiha were classified as resistant. The other studied cultivars were more or less susceptible