Infective endocarditis may be acquired in the community or in the context of health care exposure. (1) and it associated with not only cardiac complications but also renal, neurologic, musculoskeletal, and systemic complications related to the infection, such as embolization, metastatic infection, and mycotic aneurysm. Staphylococcus aureus is most frequently associated with these complications. We report a case of 41 year old man who presented with fever and developed heart failure due to multiple perforated aortic valves with aortic regurgitation. This was successfully managed by aortic valve replacement, antibiotics and hemodialysis
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