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The present study reveals allelopathic potential of aqueous leaf extracts of two invasive weeds Euphorbia hirta L. and Parthenium hysterophorus L. on seed germination, growth performance and protein content of jowar (Sorghum vulgare Pers.) seedlings. Laboratory experiments were conducted to check the allelopathic potential of aqueous extract of selected weeds on germination and seedling growth of jowar. Enfluence of aqueous extrats (25, 50, 75 and 100 % concentrations) of two weed plants were studied on seed germination, growth performance, biomass and protein content of jowar seedlings. The observations of experiments revealed a significant stimulatory allelopathic potential of both the weeds on root and shoot growth. Similar results were obtained in case of performed bioassays. Among all concentrations, 25 % concentration of both the weed extracts shows maximum stimulation in biomass and protein content in jowar seedlings.

Pathadi sura [PS] is an ayurvedic fermented formulation, prescribed for respiratory disorders. It contains Suramanda [prepared from Shali shastika tandula and Guda] and herbal drugs [Patha Murva, Rasna, Saral, Devdaru]. Compositions and therapeutic effect of PS are stated in ayurvedic classical text; however the scientific preparation method and quality parameters of PS are not documented yet. Present study is aimed to develop and validate the preparation method of PS and to generate quality standards for the formulation. Preparation of Sura and PS was done as per standard protocols of ayurvedic pharmaceutics blended with modern techniques. All herbal drugs, Sura and PS were tested with standard analytical methods. Obtained values for herbal drugs were within limits as per API standards which signify quality and purity of plant materials. Analytical profile of Sura provides quality standards and qualitative - quantitative estimation of alcohols and acids. Three batch samples of Sura and PS have shown identical values. Thus, it is concluded that the method of preparation of PS is developed and validated by using standard methods of analysis. The results obtain through this study can be used by the researchers to plan further research work on Pathadi Sura.

Objective: Brahmi Ghrita (BG) is a medicated ghee formulation, comprises of Brahmi (), Ela Bacopa monnieri () and Puran ghrita (10 years old cow ghee). It is recommended to treat broadly described mental Elettaria cardamomum illnesses especially in Unmad (Psychosis) and Apasmar (Epilepsy). However, Puran ghrita is not available in ample quantity and in current practice medicated ghee formulations are prepared with fresh go-ghrita (cow ghee). Though the potential of BG is having specific target action on brain tissue, thus to produce desired effect it should be prepared with certain standard operating procedures. Thus before initiating study, validation of manufacture process and in vivo laboratory analysis of Brahmi Ghrita prepared from Puran ghrita and fresh go-ghrita is essential. Materials and methods: In accordance to ayurvedic standard protocols, two samples of Brahmi ghrita were prepared with Puran Ghrita (BG I) and fresh cow ghee (BG II). Further validation and comparative physico-chemical analysis was done for both samples. The physico-chemical parameters such as specific gravity, moisture content, acid value, iodine Results: value, saponification value and peroxide value of BG I and BG II samples were almost alike. The process Conclusion: of manufacture and analytical values of BG I and BG II samples are validated and established in the study.

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