Soil salinity is an immense problem for agriculture. Excess amount of salt in the soil affects plant growth and development. Nearly 20% of the world's cultivated area and half of the world's irrigated lands are affected by salinity 1,2 .In hot and dry regions, most crops are grown under irrigation, and inadequate irrigation ABSTRACT Ethylene synthesis is accelerated in response to environmental stresses like salinity. Excess amount of ethylene has a negative impact on root elongation, seedlings, growth of leaves in plants. Aim of the work was study the effect of Pseudomonas mendocina containing plasmid carrying gene encoding 1-aminocyclopropane-1-carboxylate deaminase (ACD) on resistance of wheat plant under salt stress. Surface sterilized seeds of wheat plant were germinated in petri plates. Uniformly buds were selected, and were used in pot and greenhouse. Salinity as 172 and 207 mM NaCl were prepared for wheat plant in pot and 207 mM in greenhouse by irrigation of NaCl solution. acdS gene was cloned in P. mendocina and transformed bacterium was used in experiments . Results in pot experiment revealed that in 172mM salinity, cloned P. mendocina in comparison with plants treated by wild type of P. mendocina, exceeding the length of the stem by 11.6%, biomass by 43.7% and root length by % 47.5. In 207 mM NaCl results were as 2.65%, 20.6% and 11.9% respectively. Experiment in greenhouse showed that wheat plants treated by a suspension of cloned P. mendocina, in comparison with those treated by wild type of P. mendocina had 38.8% greater length of stem, 23.3% more root length and 28.6% more biomass. Wheat plants treated by cloned P. mendocina in comparison with plants without bacterial treatment had 43.8% greater length of stem, 5.5% more root length and 28.6% more biomass. It is concluded that enhancement of ACC-deaminase activity resulted in excess resistance of wheat in saline environments.