A401of which were hysterectomies. Before the launch of UPA in France, number of surgeries increased by 380 each year. The introduction of UPA was correlated with a trend reversal, showing a decrease in the number of surgeries of 1,236 each year from mid-2013. UPA did not have an impact on the type of surgery, neither on the surgical approach. The savings associated with the use of UPA pre-operatively (cost of treatment and avoided surgeries included) were estimated at 2M€ in 2013 and will reach 9M€ in 2016, that was considered as a plateau for the following years. The cumulated budgetary impact from 2016 to 2019 is estimated at -37M€ . ConClusions: Thanks to avoided surgeries, the use of UPA as pre-operative treatment is associated with financial savings, which cover largely the treatment costs. PIH10 Budget-ImPact analysIs (BIa) Of tHe IntrOductIOn Of 52mg levOnOrgestrel-releasIng IntrauterIne system (lng-Ius) as a cOntracePtIve metHOd OPtIOn In tHe BrazIlIan PuBlIc HealtHcare system (sus) tO avOId unIntended Pregnancy (uP) In 15 tO 19 year-Old adOlescents
Objetivo: O objetivo deste trabalho foi avaliar se o uso do sistema liberador de levonorgestrel (SIU- -LNG) Mirena® é custo-efetivo na prevenção de gravidez não planejada em adolescentes, entre 15 e 19 anos, quando comparado aos contraceptivos hormonais de curta duração sob a perspectiva do Sistema Único de Saúde (SUS). Métodos: Para avaliação econômica, foi elaborado um modelo de Markov, com ciclos de um ano, que acompanhou as adolescentes ao longo do curso natural do uso do método contraceptivo por um horizonte de tempo de cinco anos. Dados clínicos foram obtidos de revisão da literatura. Custos unitários foram extraídos de bases de dados oficiais. Apenas custos médicos diretos foram contemplados. Custos e benefícios foram descontados a uma taxa de 5% ao ano. Desfechos foram expressos como gravidez não planejada evitada. Resultados: Os resultados da análise de custo-efetividade mostraram que SIU-LNG é capaz de gerar economia de recursos com ganho em efetividade quando comparado com os métodos de maior prevalência de uso na adolescência (ACO e ACI). Análises de sensibilidade foram realizadas comprovando os resultados encontrados no caso-base. Conclusão: Levando-se em conta os resultados satisfatórios clínicos e econômicos, SIU-LNG deve ser considerado uma importante opção para evitar a gravidez não planejada na adolescência e todas as suas consequências.
137) of the cases returned negative results, 32% (44) of these patients were irrationally prescribed with anti-malarial drugs sans confirmed diagnosis with injectable artesunate (61%) and chloroquine (32%) for an average of 4 days resulting in 41% overdoses and 38% under doses. Direct cost associated was estimated to be USD 1,167.71. Female bedridden patients with fever and chills ≤ 3 days with normal hematological parameters, liver and renal function tests were more likely prescribed with anti-malarials. These patients had fewer co-morbidities, lower mortality, longer survival rate and longer hospitalization (p< 0.05). ConClusions: Through geriatric pharmaceutical care services, clinical pharmacist can reduce inappropriate prescribing and prevent possible adverse effects without hampering the health related quality of life.
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