A simple and convenient method for the preparation of 3-(2-(5-amino-1H-pyrazole-4-yl)thiazol-4-yl)-2H-chromene-2-one and 3-(2-(5-amino-3-methyl-1H-pyrazole-4-yl)thiazol-4-yl)-2H-chromene-2-ones (3a-f and 5a-f) have been prepared in good yields. The compounds have been synthesized from 2-(4-(2-oxo-2H-chromene-3-yl)thiazol-2yl)acetonitrile (1a-f), with DMF-DMA, DMA-DMA and hydrazine hydrochloride in ethanol resulted in the formation of title compounds. In this regard the whole compounds were tested for promising antibacterial activity, characterized by analytical and spectral data.
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