No abstract

Spreading depression (SD) of EEG activity was elicited by microinjection (5 µl) of 5% potassium chloride into the caudate nucleus (n = 7) or hippocampus (n = 3) during stereotactic brain surgery in patients with focal epilepsy. An electrode-cannula assembly for eliciting and recording the slow potential waves of SD is described. The parameters of SD in human brain are similar to those in lower mammals. Functional ablation by SD can be used as a diagnostic tool in neurosurgery.

No abstract

One-step LINAC-based SRS with a single dose 35.0 Gy is a method to treat middle-stage posterior uveal melanoma and to preserve the eye globe or as the first step of combined methods: irradiation before endoresection or cyclectomy.

Therapeutic brain stimulation was applied in 74 patients with resistant forms of epilepsy. It was shown that low frequency stimulation of certain zones of the head of the caudate nucleus and higher frequency stimulation of the dentate nucleus of the cerebellum lead to a marked suppression of interparoxysmal epileptic activity and to a disruption of both focal and generalized epileptic discharges. It is necessary to determine, by means of stereo-electroencephalography, the variability for localizing the inhibitory zones of the structures to implant the neurostimulators exactly.